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Ichthyosis is a family of rare genetic skin disorders characterized by dry, thickened, scaly skin. There are more than 20 types of ichthyosis range in severity of symptoms, outward appearance, underlying genetic cause, and mode of inheritance. Ichthyosis literally “fish”, since dry, scaly skin is the defining feature of all forms of ichthyosis.


The severity of symptoms can vary enormously, from the mildest, most common. Types such as ichthyosis vulgaris, which may be mistaken for normal dry skin, up to life-threatening conditions such as harlequin-type ichthyosis. Ichthyosis vulgaris accounts for more than 93% of cases.

Causes :

Most people with ichthyosis have inherited a particular faulty gene from their parent. Majority cases of Ichthyosis genetic disorder is responsible.


In majority of cases clinical diagnosis by external appearance of skin is possible by experienced doctor. A family history is very useful. In some cases, a skin biopsy is required to be carried out to assist the doctor to confirm the diagnosis. If requited for final diagnosis a skin biopsy and genetic testing may be useful. Disease is more found in America, Asia & other countries.